Alzheimer's drug, TGR63 molecule has been developed by scientists at the Jawaharlal Nehru Center for Advanced Scientific Research in Bangalore. Clinical trials have shown that the newly discovered drug can regenerate diseased brains, scientists say.
After more than 10 years of research, Indian Scientists discovered a possible drug that cures Alzheimer's disease
Scientists at the Jawaharlal Nehru Center for Advanced Scientific Research (JNCASR) in Bangalore are behind the world's most promising discovery. The TGR63 molecule, developed by a scientific team led by Professor T Govindaraju and an Indian-origin scientist at the KTH Royal Institute of Technology in Sweden, has been found to be able to regenerate nerve cells in the brain affected by Alzheimer's.
The team got the best results from the experiments on rats', which was a critical phase in the experiments that started in 2010. It can be given to the patient in the form of an injection or in a pill. Moreover, it is hoped that it can be used as a precaution against disease.
"After identifying the molecule we started with a test tube experiment, then tested the molecules in cellular models. We treated an Alzheimer's affected animal model and a healthy mouse with the same drug. We detected that the molecule is significantly reducing amyloid aggregates which resulted in a reversal of the cognitive decline in the animal," Govindaraju said to the Hindustan Times.
The number of Alzheimer's patients adversely affecting neurons in the human brain is estimated to exceed 5 million worldwide by 2050.